Cleave therapeutics

Developing Novel Protein Degradation Inhibitors for the Treatment of Cancer

Harnessing Innate and Adaptive Immune Responses to Cure Disease

Building upon the long-standing observation of tumor regression in the setting of bacterial infection, we have developed a unique and patented approach designed to exploit bacteria’s natural ability to fully engage the human immune system and cure disease. Our novel insights have enabled us to create proprietary, attenuated and killed non-pathogenic gram-negative bacteria that have demonstrated broad anti-tumor and anti-viral activity in pre-clinical models to date.

Cleave Therapeutics, Decoy20 Cancer Treatment Approach

This video outlines how our unique Decoy20 technology employs engineered, non-pathogenic bacteria to activate the body’s own immune defenses as a possible therapeutic against tumors.

Latest Press Release

GlobeNewswire

Sep 4, 2025 4:01 PM

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